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Thrombin
CAS No. 9002-04-4
Thrombin ( Thrombin )
Catalog No. M27107 CAS No. 9002-04-4
Thrombin is a trypsin-like allosteric serine protease.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameThrombin
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NoteResearch use only, not for human use.
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Brief DescriptionThrombin is a trypsin-like allosteric serine protease.
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DescriptionThrombin is a trypsin-like allosteric serine protease.(In Vitro):Low concentrations of thrombin and thrombin preconditioning yield the potential of rescuing cells and to induce survival of neurons and astrocytes exposed to various ischemic insults.(In Vivo):Elevated thrombin activity was found in the brain slices from mice that were treated (in vitro and in vivo) with paraoxon. Increased levels of PAR-1 and pERK proteins and decreased prothrombin mRNA were found in the brains of paraoxon-treated mice. Furthermore, ex vivo and in vivo electrophysiological experiments showed that exposure to paraoxon causes elevated electrical activity in CA1 and CA3 regions of the hippocampus. Moreover, a specific PAR-1 antagonist (SCH79797) reduced this activity. Altogether, these results reveal the importance of thrombin and PAR-1 in paraoxon poisoning.
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In Vitro——
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In Vivo——
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SynonymsThrombin
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PathwayAutophagy
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TargetThrombin
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Recptorneuropeptide Y (NPY) Y1 receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number9002-04-4
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Formula Weight37kDa
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Molecular Formula——
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Kokare DM, et, al. Interaction between neuropeptide Y and alpha-melanocyte stimulating hormone in amygdala regulates anxiety in rats. Brain Res. 2005 May 10;1043(1-2):107-14.
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